PCL Collagen Biostimulators | Radium Medical Aesthetics

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Aesthetic Treatments

PCL Collagen Bio-Stimulating Fillers

Collagen Bio-Stimulating Dermal Fillers For Anti-Ageing

PCL collagen bio-stimulating fillers provide long-lasting and sustained correction by volumisation and stimulating collagen production from within the skin.

It works differently from traditional dermal fillers, which work by directly filling in a wrinkle or volume deficiency using hyaluronic acid. On the other hand, this type of collagen bio-stimulating fillers contain a biodegradable synthetic material called polycaprolactone, or PCL. It stimulates your body’s own collagen to correct volume loss, wrinkles and folds – treating the underlying causes of facial ageing at its root. As a result, you can expect a natural, youthful appearance with long-lasting effects. 

Woman receiving injectable treatment

Which PCL Collagen Bio-Stimulating Filler Is safe for use in Singapore?

At Radium, the type of PCL collagen bio-stimulator we are using is Ellanse, which is approved for use in Singapore. 

Ellanse is made of a biodegradable synthetic material, precisely engineered microspheres and homogeneously suspended in a tailor-made aqueous Carboxy-methylcellulose (CMC) gel-carrier. The carbooxymethyl cellulose is the component that provides the plumping effect, and polycaprolactone provides the sustained effect. It was developed in 2006 in The Netherlands and obtained the CE mark in 2009, KFDA registration in 2013 in South Korea, the TGA in Australia.

In 2017, a study was conducted by the manufacturer to emphasize the various safety aspects of Ellanse. The CMC is classified as Generally Recognized As Safe substance in food additives by the US FDA. On the other hand, it was noted that PCL is a widely used compound in many medical devices for several decades. Since it obtained CE Mark in 2009, 300,000 syringes have been administered globally with little report of adverse events.

How does the treatment work?

The treatment is able to provide long-term collagen stimulation. It helps the skin regain what was naturally lost with age. Therefore, once the CMC component have been reabsorbed by the body, you will still enjoy beneficial, long-lasting effects from the PCL that is present in it.

How long does it last?

The immediate results you get after the treatment can last from anywhere between 1 and 4 years. As the results are long-lasting compared to regular dermal fillers, you do not need to go for follow-up visits with the doctor for multiple sessions. Hence, it is an economical solution to improve your facial contours and look more youthful.

PCL collagen bio-stimulators is a very popular skin rejuvenation treatment in Singapore because it does not only plump up deficient areas of the face but it also stimulates collagen production from within, resulting in longer-lasting effects.

Does The Treatment have any risk or side effects?

As with other dermal filler injections, itching and swelling can be expected immediately after the treatment. You can also expect localised swelling and redness at the injection sites. However, these mild side effects should subside within 1-2 days and you can return to your daily activities.

Can The Treatment be reversed or dissolved?

Unfortunately, PCL collagen bio-stimulators are not the same as hyaluronic acid fillers and cannot be dissolved. This means that once it is injected into your body, it is non-reversible. You will have to wait for 2-3 years for the filler to naturally break down in your body. Therefore, it is very important to consider very carefully before opting to undergo the treatment. Choosing an experienced doctor to administer the treatment for you to ensure that you achieve the best possible outcome.

Why Choose Radium For Ellanse Treatment?

Our Medical Director, Dr. Siew Tuck Wah, is an accredited Ellanse Filler Trainer. 

He attended the Ellanse Trainers’ Accreditation and is certified as an Ellanse Trainer in May 2017. He has undergone extensive training in the use of Ellanse fillers to achieve the best results for patients in the safest possible manner.


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    Achieve visible skin lifting and plumping effects
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    Observe skin revitalisation and firmness through natural collagen stimulation
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    Reshape facial contours to achieve desired, long-lasting results
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    Reverse and delay signs of skin ageing
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    Only 1 treatment is required which will last for 2-3 years

Best For

Those who want to use this collagen stimulator to erase deep folds around the mouth and nose, sunken cheeks, facial scars. It is also a good choice for those who want to sculpt and shape the nose as this filler lasts longer than most fillers.

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