PDRN Skin Therapy
Kickstart Skin Repair with DNA-based injectable
Polydeoxyribonucleotides (PDRN) is a compound that possesses several unique therapeutic properties such as to heal wounds, repair skin tissue and reduce inflammation. In fact, doctors have been using PDRN as an effective treatment for tissue repair in peripheral artery occlusive diseases and diabetic foot ulcers. PDRN contains DNA extract of salmon. Other than providing health benefits, salmon DNA has several anti-ageing benefits. Studies have shown that salmon DNA is an important key ingredient for repairing and rejuvenating the skin. PDRN is well-known for its ability to stimulate cell growth that accelerates cell proliferation and regeneration of skin and tissue. In fact, there were studies to support the findings that PDRN is beneficial for regeneration of skin and tissue. Further studies also suggested that PDRN accelerates the repair and growth of bone tissue and encourages the skin repair process in diabetic animals.
How is PDRN Injection Administered?
PDRN injection is usually administered by a doctor using a series of small, precise injections into the skin. After the treatment area is cleansed and prepared, a numbing cream may be applied to improve comfort. The PDRN solution is then delivered into targeted areas using fine needles, commonly across the face, neck, under-eye area, or other areas where skin repair, hydration, and rejuvenation are desired.
The injection technique may vary depending on the patient’s skin condition and treatment goals. In some cases, PDRN may be placed superficially into the skin to improve overall skin quality, while in other cases, it may be injected into specific areas that require more focused repair or rejuvenation. Mild redness, small bumps, swelling, or bruising may occur after treatment, but these usually settle over the next few days.
A consultation is recommended before treatment so the doctor can assess your skin condition, suitability, and the number of sessions required. Results vary between individuals, and repeated sessions may be recommended for more sustained improvement.
How does PDRN Treatment Benefit me?
PDRN treatment may benefit the skin by supporting repair, hydration, and overall skin rejuvenation. PDRN, or polydeoxyribonucleotide, is commonly used in aesthetic medicine to help improve skin quality by encouraging the skin’s natural recovery processes and supporting a healthier skin environment.
For patients with dull, tired, dehydrated, or ageing skin, PDRN injections may help to improve skin texture, elasticity, and radiance over time. It may also be useful for skin that appears stressed, sensitive, or weakened, as the treatment is often used to support skin healing and regeneration.
Results vary between individuals and usually develop gradually. A series of sessions may be recommended depending on your skin condition, treatment goals, and whether PDRN is combined with other treatments such as lasers, skinboosters, microneedling, or other regenerative injectables.
Rejuran Healer and PDRN: what's the difference?
Rejuran Healer is a brand of PDRN. This is similar to botulinum toxin. People often simply refer botulinum toxin Type A as Botox, but Botox is actually a well-known brand name of botulinum toxin for treating fine lines and wrinkles. Rejuran utilizes PDRN extracted from salmon DNA to stimulate new skin cell growth and collagen production. After it is injected into the skin, it leads to a rapid renewal of the skin, providing a host of benefits that are often associated with youthful skin. Both offer similar benefits.
Is PDRN A dermal Filler?
No. PDRN is not considered a dermal filler.
Dermal fillers are typically used to restore volume, enhance facial contours, or fill lines and folds. PDRN, on the other hand, is a skin rejuvenation and regenerative treatment that focuses on improving skin quality from within.
PDRN works by supporting the skin’s natural repair process, helping to improve hydration, elasticity, texture, and overall skin health over time. It does not create significant volume or structural lift in the way hyaluronic acid fillers or collagen biostimulating fillers may do.
In simple terms:
Dermal fillers = volume and contour
PDRN = repair, hydration, and skin quality
Depending on your concerns, PDRN may be recommended on its own or combined with other treatments such as lasers, skinboosters, microneedling, or dermal fillers for a more comprehensive rejuvenation plan.
Benefits
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Kickstart intense skin repair and speed up wound healing -
Improve overall skin texture and skin tone -
Reduce appearance of fine lines and wrinkles -
Reduce skin laxity by stimulating collagen production -
Reduce appearance of pigmentation
Best For
Men and women who want to achieve younger-looking skin without undergoing surgical procedure. PDRN injectable is a suitable non-surgical procedure that allows ageing skin to undergo cell renewal and new cell growth so as to achieve brighter, fairer, skin with less visible fine lines and wrinkles.
This treatment is also suitable for people who have small scars on the face as PDRN injectable helps to accelerate wound healing with brilliant results.




